Tetracycline is not often used topically, but rather as an oral antibiotic. You can also use it as a solution or ointment at different strengths. Tetracycline contains sodium bisulfite, derived from sulfa. It can cause an allergic reaction and may cause yellowing of the skin. However, it's popular as an oral antibiotic with dermatologists. It may have the same side effects as the other two.
When sebum can no longer reach the skin surface, it clogs up the gland in such a way that greasy or cheesy plugs are formed. Aside from being unsightly, these plugs or whiteheads may later be infected and leave scars when tampered with. Some undergo chemical changes and become blackheads.
Another popular acne treatment is Retin-A. Tretinoin, or Retin-A, first became popular in the 1980's. This topical treatment is a derivative of vitamin A and is best used to treat blackheads and whitehead type acne. Retin-A works to remove whatever is clogging the pore and then also will prevent new whiteheads or blackheads from forming. In recent years, this chemical has also been found to improve wrinkles and is being used by those who wish to look younger.
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